While looking for a handy dandy chart that I have some place showing an LC-50 for 300ppm equating to half an hour (this chart too is likely dubious) I noticed that Germar in The Chemistry of Auschwitz made a formula that can be used to calculate lethal concentrations which conforms roughly to real world data from American Gas Executions.


This can be found on page 234 of The Chemistry of Auschwitz, although the whole section is worth reading beginning from page 230.
Needless to say, the supposed 300ppm, while conforming to OSHA safety guidelines, is quite conservative when balanced against execution data.
I don't recall the forum having a thread on this so I leave it here for posterity.